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Drug induced liver disease

DESCRIPTION Drug induced liver disease is very common and is the most frequent cause of drug withdrawal following post-marketing surveillance. For many drugs, patterns of hepatic toxicity do not become apparent until they have been widely used in clinical practice. Hepatotoxicity is also frequently observed with established drugs and is major cause of drug related morbidity and mortality.

HERBS OF CHOICE Herbs are often used in combinations when combating an illness. Some of the most frequently used herbs are listed below. These nine herbs were picked up from different herbal combinations and are not meant to form a recipe. Our reference code for the different combinations of herbs used for this condition is DLD. This listing is not meant to diagnose, only to inform. This is of course not a complete list and is not meant to be used in the place of a doctor's advice. Click the image of each herb for a brief introduction in terms of Traditional Chinese Medicine.
CLINICAL SUCCESS IN CHINA Chinese herbal doctors have reported some successful applications of these herbal combinations. In comparative study on 128 patients random divided into two groups:
  • Herb-treated group: receiving treatment with herbal remedy in addition to conventional treatment
  • Control group: receiving conventional treatment
the therapeutic effect in the herb-treated group was much better than that in the control group as a result. Besides, no obvious adverse reactions were found in the herb-treated group. Check the table below for details.
Cases
Total effective
cases
%
Herb-treated
68
63
92.6
Control group
60
45
75.0
HERBAL REMEDY BEST FOR YOU The most powerful feature of Traditional Chinese Medicine is that it allows you to easily combine multiple ingredients to form a recipe to suit the specific need of individual. The list below are to give you an idea of why you can get the herbal remedy best for you from here with us.

Authoritative Oriented Recipes: All these well chosen herbal combinations source from experienced and authoritative experts, and have been most commonly recognized by the practitioners in this field. When you choose a herbal remedy there are two important things among your concerns: a good recipe and a correct way to cook it. A good recipe is half the good results.

Custom-made with Unique Technology: When you order a herbal remedy at this website you can figure out your symptoms by using our online questionnaire system. In this way a basic herbal recipe could be customized and optimized by adding or removing some herbs to address the individual symptoms exactly. Chinese herbs should not be used in form of standard industrial products manufactured in bulk to cope with all body issues. Only custom-made is the traditional and professional way to use Chinese herbs. All the herbal remedies available at this website are purposed to be custom-made on each single order base. With our unique technology called Low-temperature Concentration the active ingredients of herbs could be survival as much as possible while being concentrated. Eevery 8 ml of the extracts, as one dose, might equal to about 50 grams of raw herbs.
Safe and Side Effect Free: All these herbs have been being used in China for thousands of years, and have been proven to be safe. In fact most Chinese herbs are tonics without side effects. What important is that experienced practitioners should know how to use herbs to avoid possible side effects.
Easy-to-Take Dosage Form: You do NOT need to cook these herbs at all. We get everything ready for you. The herbal remedy comes with the preparation in an easy-to-take dosage form, typically an oral dosage form namely Liquid Herbal Extracts created on a single order base. If necessary other dosage forms, such as pills, capsules, tablets, powder, tea bag, agar gel, rinse, lotion, spray, tincture, liniment, ointment, suppositories, etc., might be used depending on how to use the herbs correctly. And herbal remedy kit, consisting of two different herbal formulae typically one for oral administration and another for external use, is often used for the skin conditions.
Low-cost Customized Service: Two month's supply of this custom-made herbal preparation created on a single order base costs US$299.95 only. It is the average duration to take the remedy for an effect recommended for most individuals with different responses. Shipping charges are not included in the purchase price and will depend upon the shipping method that you choose. Please read our Shipping Policy for details. No any other hidden fees. Click the button below to go to questionnaire and order this herbal remedy.
Drug-induced liver disease may account for between 10% and 50% of adult patients with elevated enzymes, especially in patients over age 50 years. It accounts for nearly 25% of patients with fulminant hepatic failure. Liver injury can be cytotoxic, cholestatic, or mixed. A variety of systemic manifestations can accompany drug-induced hepatotoxicity. Drug-induced liver disease can mimic autoimmune hepatitis or it can evolve to cirrhosis. It can also mimic veno-occulusive disorders.
Drug induced liver disease is a common cause of abnormal liver enzymes and liver injury because many drugs are metabolized through the liver. This type of liver disease is of increasing concern because of all the over the counter supplements that may have impurities in them.
Type and example:
  • Acute hepatocellular injury
    • Toxic necrosis (e.g., CCl4,acetaminophen)
    • Hepatitis-like (e.g.,isoniazid, methyldopa)
  • Cholestasis
    • Inflammatory (e.g.,chlorpromazine)
    • Pure (e.g., oral contraceptives)
  • Miscellaneous acute/subacute
  • Chronic liver disease
    • Chronic hepatitis (e.g., isoniazid, methyldopa)
    • Chronic cholestasis (e.g., chlorpromazine)
    • Fibrosis/cirrhosis (e.g., methotrexate)
    • Tumor: adenomas (oral contraceptives)
SYNONYMS
  • Drug induced liver injury; DILI; DILD
  • Toxic liver disease
SYMPTOMS Signs and symptoms of liver disease are diverse. Some of the symptoms of liver disease include fatigue, decreased appetite, impaired sense of taste or smell, nausea, weight loss, abdominal distress, and sexual dysfunction. Some of the physical signs of liver disease may be yellowness of the skin (jaundice), low grade fever, swelling of the abdomen or ankles (edema), dilated arterial blood vessels on the skin (spiders), muscle wasting, and loss of body hair.
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